Patent 2003271352

Electronic detection of nucleic acids using monolayers

Abstract

(12) STANDARD PATENT APPLICATION (11) Application No. AU 2003271352 Al (19) AUSTRALIAN PATENT OFFICE (54) Title Electronic detection of nucleic acids using monolayers (51)7 International Patent Classification(s) C12Q 001/68 G01N 027/30 C07F 017/00 C07F 017/02 (21) Application No: 2003271352 (22) Date of Filing: 2003.12.24 (43) Publication Date: 2004.02.05 (43) Publication Journal Date: 2004.02.05 (62) Divisional of: 765597 (71) Applicant(s) Clinical Micro Sensors, Inc. (72) Inventor(s) Yu, Changyun; Bamdad, Cynthia (74) Agent Attorney Davies Collison Cave, 1 Little Collins Street, MELBOURNE, VIC, 3000 ABSTRACT A composition comprising; a) an electrode comprising: a monolayer comprising conductive oligomers; and (ii) a capture probe; b) a target sequence comprising a first portion that is capable of hybridizing to said capture probe, and a second portion that does not hybridize to said capture probe and comprises at least one covalently attached electron transfer moiety. A composition comprising: a) an electrode comprising: i) a monolayer comprising conductive oligomers; and ii) a capture probe; b) a label probe comprising a first portion that is capable of hybridizing to a component of an assay complex and a second portion comprising a recruitment linker that does not hybridize to a component of an assay complex and comprises at least one covalently attached electron transfer moiety. Methods of using the above are also claimed.

Information

Australian application number
2003271352
Country
US
Status
Lapsed
Type
Standard
Applicant
Clinical Micro Sensors, Inc., INC (US)
Application year
2003

International Patent Classification (IPC) codes

Links

ID Relationship
1999024735 Divisional parent